This is a call from the "gedolim" to the bochurim (I added quotes on gedolim only because I have never heard of any of these rabbis) to not go collecting on Purim in houses because women are there. The boys should only go collecting where it is known that no women are present. They also call upon the baalebatim to ensure the rules of modesty are kept in the homes and that the women should not hang around in places where there are men...

The sign looks real and not like a joke, but having never heard of these rabbis I can't be sure, and they may be fake names.

I guess the other option was to tell the husbands to kick their wives out of the house for Purim so the boys could come collecting....